3. Autoimmune Diseases
Patients who are dealing with autoimmune diseases find that the body creates antibodies and white blood cells that attack healthy cells within the body. An example of this condition is rheumatoid arthritis, where the immune system confuses healthy cells in the bones and joints, with invading pathogens. As a result, the brain signals the hypothalamus to create antibodies and white blood cells to attack the healthy cells, resulting in symptoms of extreme pain in the affected individual.
Other inflammatory disorders, such as gout, may also have a similar effect in creating symptoms of pain. People who experience the onset of gout have a buildup of uric acid crystals in the joint, limiting the range of motion, producing symptoms of pain when flexing the affected area.
If left unmanaged and untreated, the symptoms of inflammatory diseases will continue to escalate. Eventually, the patient may start to develop symptoms of enthesopathy, resulting in the onset of the condition.