{"id":10724,"date":"2019-09-08T06:53:19","date_gmt":"2019-09-08T06:53:19","guid":{"rendered":"https:\/\/simplyhealth.io\/?p=10724"},"modified":"2021-06-29T19:31:22","modified_gmt":"2021-06-29T19:31:22","slug":"15-common-causes-of-calciphylaxis","status":"publish","type":"post","link":"https:\/\/simplyhealth.io\/15-common-causes-of-calciphylaxis\/","title":{"rendered":"15 Common Causes of Calciphylaxis"},"content":{"rendered":"\n
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Calciphylaxis, a rare condition that affects the kidneys is one that should be taken seriously. This condition allows the calcium to buildup in the blood vessels of the skin and fat. It is also often referred to as calcific uremic arteriolopathy. Usually, those who suffer from chronic kidney disease present with calciphylaxis. It can also develop in those who are taking dialysis due to kidney failure, and those who have undergone a kidney transplant. Calciphylaxis also causes painful skin lesions to develop as well as allowing calcium to build up in the blood. <\/p>\n\n\n\n

Another common side effect of the condition is severe infections that frequently prove fatal. Calciphylaxis also encourages the formation of skin ulcers and blood clots. These skin ulcers are often the cause of several serious infections. <\/p>\n\n\n\n

Calciphylaxis is mostly found in people who are suffering from conditions that affect the kidney, however, in rare instances, the ailment may develop in those who are not afflicted with kidney disease. <\/p>\n\n\n\n

1. Blood-clotting factor abnormalities<\/strong> <\/h3>\n\n\n\n

In general, there is no specific cause for calciphylaxis, medical science has it currently listed as unknown. The majority of patients who suffer from calciphylaxis, however, have been noted to have blood-clotting factor abnormalities. Blood-clotting factors are an essential part of your blood makeup. \u00a0These are one of the key substances in your blood <\/a>that help you to stop bleeding when you are injured. <\/p>\n\n\n\n

Without blood clotting factors, your body will be unable to heal itself after an injury which may result in bleeding to death. Certain blood-clotting factor abnormalities work in the opposite fashion. Instead of simply helping your body to heal by clotting the blood that the site of a wound, it causes the blood to hyper-clot. <\/p>\n\n\n\n

When blood-clotting factor abnormalities come into play, they trigger the formation of small blood clots in the bloodstream. These clots are formed even in the absence of a wound and form in higher concentrations than usual.<\/p>\n\n\n\n\n\n\n\n

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2. Hypercalcemia <\/strong><\/h3>\n\n\n\n

Too much calcium in the blood is a serious condition called Hypercalcemia<\/a>. We need calcium in order to function properly, but too much has a detrimental effect. One of the most common causes of calciphylaxis is Hypercalcemia. Those who are suffering from Hypercalcemia may also experience weak bones and a higher than usual amount of kidney stones. <\/p>\n\n\n\n

Hypercalcemia also has a negative effect on the brain and heart. When there is too much calcium in your blood it can cause a wide range of problems for your kidney other than just Hypercalcemia. <\/p>\n\n\n\n

Most of the time this condition occurs when the parathyroid glands become overactive. These small glands sit behind your thyroid are tasked with regulating the amount of calcium in your blood. Hypercalcemia can cause calciphylaxis and it can also be a symptom of calciphylaxis, in many instances a person may be totally unaware that they have a calcium buildup in their blood.  <\/p>\n\n\n\n\n\n\n\n

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3. Calcium metabolism imbalance<\/strong><\/h3>\n\n\n\n

One of the key causes of calciphylaxis are conditions that cause calcium metabolism <\/a>to become imbalanced. Your body needs calcium in order to function. It helps keep your teeth and bones strong along with various other functions in the body. When there is an imbalance in the way your body metabolizes calcium, it can lead to complications such as calciphylaxis. Improperly metabolized calcium often finds its way into the smallest arterioles. <\/p>\n\n\n\n

Too much calcium will trigger the development of blood clots in these arteries. Blood clots are basically clumps that have failed to dissolve for whatever reason. These random blood clots can be dangerous. They can prevent the tissues in your skin from getting the nourishment and oxygen they need to function properly. <\/p>\n\n\n\n

Blood clots can also deprive the fat tissues in your system from receiving essential nutrients and fresh oxygen. Calciphylaxis is caused by an imbalance that results in the disruption of how calcium is metabolized.<\/p>\n\n\n\n\n\n\n\n

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4. Autoimmune conditions<\/strong><\/h3>\n\n\n\n

There are several autoimmune conditions that can cause calciphylaxis to develop. Conditions such as systemic lupus erythematosus\u00a0are one of the prime causes, while Crohn\u2019s disease<\/a> is one of the next most common autoimmune condition causes. rheumatoid arthritis is also another common cause of calciphylaxis in older patients. Each of these autoimmune conditions affects how calcium is stored in your bloodstream which results in calciphylaxis and other kidney-related ailments. <\/p>\n\n\n\n

Your parathyroid glands regulate most of the calcium in your blood, when this process is disturbed it can lead to a myriad of illnesses such as calciphylaxis and other complications. Some autoimmune conditions that cause calciphylaxis are hereditary while others may develop later in life. <\/p>\n\n\n\n

If you suffer from a condition of the autoimmune system that may result in calciphylaxis or other kidney diseases, it is important that you undergo regular testing to help manage the negative side effects of the condition.  <\/p>\n\n\n\n\n\n\n\n

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5. Hyperphosphatemia<\/strong>  <\/h3>\n\n\n\n

Your body hosts a wide range of electrolytes, phosphate is one of them. This electrolyte carries a small electric charge and converts into phosphorus which is essential for your health. It is possible to have too much phosphate in your blood, when that happens it is called hyperphosphatemia. One of the more common causes of calciphylaxis is hyperphosphatemia, though each condition can lead to the other or develop as completely unrelated issues. <\/p>\n\n\n\n

You need phosphate in your body to strengthen your bones and to generate energy but too much in your bloodstream <\/a>can cause muscle cramps, strokes and heart attacks. When a person suffers from kidney damage, one of the first changes that happen to the blood is an increase in phosphate levels. <\/p>\n\n\n\n

This change can trigger calciphylaxis if it was not already present. The kidneys help to maintain the proper levels of phosphate in the blood, when the kidneys are damaged, calciphylaxis is not far behind.<\/p>\n\n\n\n\n\n\n\n

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6. Cancer<\/strong> <\/h3>\n\n\n\n

All forms of cancer <\/a>are a perversion of cells in the body that change from their original purpose to grow without restriction and eventually become life-threatening tumors. Cancer often caused other conditions such as calciphylaxis. Cancer is a perversion of the cells already present in the body and the perversion is initiated in the body most often by the introduction of the various chemicals in the environment over a period of time. Not all people who are exposed to toxins get cancer and not all cancer patients who have cancer have been exposed. <\/p>\n\n\n\n

There are four stages of cancer, the first two being the most treatable however most cancer cases are not caught until the latter stages. Understanding what to look for plays a big role in finding cancer early on and can mean the difference in life expectancy. Even with early treatment, cancer many cause calciphylaxis to develop.<\/p>\n\n\n\n\n\n\n\n

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7. Primary Hyperparathyroidism<\/strong> <\/h3>\n\n\n\n

There are several conditions that can lead to calciphylaxis, most of those are found in patients who have some form of a kidney condition. The kidney <\/a>is responsible for filtering the blood, when it is unable to do so, it can cause the blood to become toxic. The parathyroid glands secrete a hormone into the blood, when they become overactive it causes the amount of calcium in the bloodstream to increase excessively. <\/p>\n\n\n\n

When there is too much calcium in the blood that is not filtered out, it can trigger the development of calciphylaxis. Most patients who have calciphylaxis suffer from kidney problems, but not all of them. Hyperparathyroidism directly results in an increase in calcium in the blood, which causes calciphylaxis. <\/p>\n\n\n\n

Untreated hypercalcemia can lead to bone thinning, calciphylaxis, and other complications. Treatment usually involves medication or in serious cases, surgery. Calciphylaxis can be reversed in hypercalcemia patients who do not have a kidney condition.<\/p>\n\n\n\n\n\n\n\n

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8. Kidney disease<\/strong> <\/h3>\n\n\n\n

Calciphylaxis is caused by a wide range of ailments but is most often seen in patients who are suffering from some sort of kidney condition. Kidney disease\u00a0is a condition in which the kidneys have become damaged to the point where they are unable to filter your blood properly. Kidney disease can cause calciphylaxis, hyperparathyroidism, Hyperphosphatemia, and a wide assortment of other ailments. Those who suffer from high blood pressure or diabetes <\/a>are more at risks of later developing kidney failure and calciphylaxis. <\/p>\n\n\n\n

The most common treatment for kidney failure is dialysis or a total transplant. Calciphylaxis is a disruption in mineral metabolism of calcium in the blood, while this can be caused by kidney disease, the condition is also found in patients who don\u2019t exhibit any form of a kidney condition. There are five stages of chronic kidney disease and each stage carries the risks of triggering the condition calciphylaxis.<\/p>\n\n\n\n\n\n\n\r\n

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